Negative Regulation of TLR Signaling by BCAP Requires Dimerization of Its DBB Domain

The B cell adaptor protein (BCAP) is a multimodular regulator of inflammatory signaling in diverse immune system cells. BCAP couples TLR signaling to phosphoinositide metabolism and inhibits MyD88-directed signal transduction. BCAP is recruited to the TLR signalosome forming multitypic interactions...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Immunol
Egile Nagusiak: Lauenstein, Johannes U., Scherm, Michael J., Udgata, Atul, Moncrieffe, Martin C., Fisher, David I., Gay, Nicholas J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: AAI 2020
Gaiak:
Molecular and Structural Immunology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7128310/
https://ncbi.nlm.nih.gov/pubmed/32198144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1901210
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak