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Apoptosis and autophagy in polycystic kidney disease (PKD)

Apoptosis in the cystic epithelium is observed in most rodent models of polycystic kidney disease (PKD) and in human autosomal dominant PKD (ADPKD). Apoptosis inhibition decreases cyst growth, whereas induction of apoptosis in the kidney of Bcl-2 deficient mice increases proliferation of the tubular...

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Publié dans:Cell Signal
Auteurs principaux: Nowak, Kristen L., Edelstein, Charles L.
Format: Artigo
Langue:Inglês
Publié: 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7127985/
https://ncbi.nlm.nih.gov/pubmed/31881325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2019.109518
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