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Apoptosis and autophagy in polycystic kidney disease (PKD)

Apoptosis in the cystic epithelium is observed in most rodent models of polycystic kidney disease (PKD) and in human autosomal dominant PKD (ADPKD). Apoptosis inhibition decreases cyst growth, whereas induction of apoptosis in the kidney of Bcl-2 deficient mice increases proliferation of the tubular...

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Bibliografiske detaljer
Udgivet i:Cell Signal
Main Authors: Nowak, Kristen L., Edelstein, Charles L.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7127985/
https://ncbi.nlm.nih.gov/pubmed/31881325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2019.109518
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