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To clear or to fear: An innate perspective on factor VIII immunity

The enigma that is factor VIII immunogenicity remains ever pertinent in the treatment of hemophilia A. Development of neutralizing antibodies against the therapeutic protein in 25–30% of patients likely depends on the appropriate activation of the innate immune response shortly following antigen enc...

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Detalhes bibliográficos
Publicado no:Cell Immunol
Main Authors: Lai, Jesse Derek, Georgescu, Maria Teofana, Hough, Christine, Lillicrap, David
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7124272/
https://ncbi.nlm.nih.gov/pubmed/26547364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellimm.2015.10.011
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