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Alloantibodies to therapeutic factor VIII in hemophilia A: the role of von Willebrand factor in regulating factor VIII immunogenicity

The rising incidence of neutralizing antibodies (inhibitors) against therapeutic factor VIII prompted the conduct of studies to answer the question as to whether this rise is related to the introduction of recombinant factor VIII products. The present article summarizes current opinions and results...

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Detalhes bibliográficos
Publicado no:Haematologica
Main Authors: Oldenburg, Johannes, Lacroix-Desmazes, Sébastien, Lillicrap, David
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4803147/
https://ncbi.nlm.nih.gov/pubmed/25638804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2014.112821
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