Elevated Type 1 Metabotropic Glutamate Receptor Availability in a Mouse Model of Huntington’s Disease: a Longitudinal PET Study

Impairment of group I metabotropic glutamate receptors (mGluRs) results in altered glutamate signalling, which is associated with several neurological disorders including Huntington’s Disease (HD), an autosomal neurodegenerative disease. In this study, we assessed in vivo pathological changes in mGl...

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Udgivet i:Mol Neurobiol
Main Authors: Bertoglio, Daniele, Verhaeghe, Jeroen, Korat, Špela, Miranda, Alan, Cybulska, Klaudia, Wyffels, Leonie, Stroobants, Sigrid, Mrzljak, Ladislav, Dominguez, Celia, Skinbjerg, Mette, Liu, Longbin, Munoz-Sanjuan, Ignacio, Staelens, Steven
Format: Artigo
Sprog:Inglês
Udgivet: Springer US 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7118044/
https://ncbi.nlm.nih.gov/pubmed/31912442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-019-01866-5
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