Validation and noninvasive kinetic modeling of [(11)C]UCB-J PET imaging in mice

Synaptic pathology is associated with several brain disorders, thus positron emission tomography (PET) imaging of synaptic vesicle glycoprotein 2A (SV2A) using the radioligand [(11)C]UCB-J may provide a tool to measure synaptic alterations. Given the pivotal role of mouse models in understanding neu...

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Publicado en:J Cereb Blood Flow Metab
Autores principales: Bertoglio, Daniele, Verhaeghe, Jeroen, Miranda, Alan, Kertesz, Istvan, Cybulska, Klaudia, Korat, Špela, Wyffels, Leonie, Stroobants, Sigrid, Mrzljak, Ladislav, Dominguez, Celia, Liu, Longbin, Skinbjerg, Mette, Munoz-Sanjuan, Ignacio, Staelens, Steven
Formato: Artigo
Lenguaje:Inglês
Publicado: SAGE Publications 2019
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Original Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7232782/
https://ncbi.nlm.nih.gov/pubmed/31307287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0271678X19864081
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