Elevated Type 1 Metabotropic Glutamate Receptor Availability in a Mouse Model of Huntington’s Disease: a Longitudinal PET Study

Impairment of group I metabotropic glutamate receptors (mGluRs) results in altered glutamate signalling, which is associated with several neurological disorders including Huntington’s Disease (HD), an autosomal neurodegenerative disease. In this study, we assessed in vivo pathological changes in mGl...

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Gepubliceerd in:Mol Neurobiol
Hoofdauteurs: Bertoglio, Daniele, Verhaeghe, Jeroen, Korat, Špela, Miranda, Alan, Cybulska, Klaudia, Wyffels, Leonie, Stroobants, Sigrid, Mrzljak, Ladislav, Dominguez, Celia, Skinbjerg, Mette, Liu, Longbin, Munoz-Sanjuan, Ignacio, Staelens, Steven
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Springer US 2020
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7118044/
https://ncbi.nlm.nih.gov/pubmed/31912442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-019-01866-5
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