Elevated Type 1 Metabotropic Glutamate Receptor Availability in a Mouse Model of Huntington’s Disease: a Longitudinal PET Study

Impairment of group I metabotropic glutamate receptors (mGluRs) results in altered glutamate signalling, which is associated with several neurological disorders including Huntington’s Disease (HD), an autosomal neurodegenerative disease. In this study, we assessed in vivo pathological changes in mGl...

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Pubblicato in:Mol Neurobiol
Autori principali: Bertoglio, Daniele, Verhaeghe, Jeroen, Korat, Špela, Miranda, Alan, Cybulska, Klaudia, Wyffels, Leonie, Stroobants, Sigrid, Mrzljak, Ladislav, Dominguez, Celia, Skinbjerg, Mette, Liu, Longbin, Munoz-Sanjuan, Ignacio, Staelens, Steven
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer US 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7118044/
https://ncbi.nlm.nih.gov/pubmed/31912442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-019-01866-5
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