Kinetic Modelling and Test–Retest Reproducibility for the Dopamine D(1)R Radioligand [(11)C]SCH23390 in Healthy and Diseased Mice

PURPOSE: Our aim in this study was to compare different non-invasive pharmacokinetic models and assess test–retest reproducibility of the radioligand [(11)C]SCH23390 for the quantification of dopamine D(1)-like receptor (D(1)R) in both wild-type (WT) mice and heterozygous (HET) Q175DN mice as Huntin...

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Enregistré dans:
Détails bibliographiques
Publié dans:Mol Imaging Biol
Auteurs principaux: Bertoglio, Daniele, Verhaeghe, Jeroen, Miranda, Alan, Wyffels, Leonie, Stroobants, Sigrid, Dominguez, Celia, Munoz-Sanjuan, Ignacio, Skinbjerg, Mette, Liu, Longbin, Staelens, Steven
Format: Artigo
Langue:Inglês
Publié: Springer International Publishing 2020
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7910372/
https://ncbi.nlm.nih.gov/pubmed/33179158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11307-020-01561-1
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