Calcitriol prevents RAD51 loss and cGAS-STING-IFN response triggered by progerin

Hutchinson Gilford Progeria Syndrome (HGPS) is a devastating accelerated aging disease caused by LMNA gene mutation. The truncated lamin A protein produced “progerin” has a dominant toxic effect in cells, causing disruption of nuclear architecture and chromatin structure, genomic instability, gene e...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Proteomics
Egile Nagusiak: Coll-Bonfill, Nuria, de Faria, Rafael Cancado, Bhoopatiraju, Sweta, Gonzalo, Susana
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2019
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7117971/
https://ncbi.nlm.nih.gov/pubmed/31834988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pmic.201800406
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