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Genomic instability and innate immune responses to self-DNA in progeria
In the last decade, we have seen increasing evidence of the importance of structural nuclear proteins such as lamins in nuclear architecture and compartmentalization of genome function and in the maintenance of mechanical stability and genome integrity. With over 400 mutations identified in the LMNA...
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| Vydáno v: | GeroScience |
|---|---|
| Hlavní autoři: | , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Springer International Publishing
2019
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6702534/ https://ncbi.nlm.nih.gov/pubmed/31280482 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-019-00082-2 |
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