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Causes and consequences of genomic instability in laminopathies: Replication stress and interferon response

Mammalian nuclei are equipped with a framework of intermediate filaments that function as a karyoskeleton. This nuclear scaffold, formed primarily by lamins (A-type and B-type), maintains the spatial and functional organization of the genome and of sub-nuclear compartments. Over the past decade, a b...

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Detalhes bibliográficos
Publicado no:Nucleus
Main Authors: Graziano, Simona, Kreienkamp, Ray, Coll-Bonfill,, Nuria, Gonzalo, Susana
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5973265/
https://ncbi.nlm.nih.gov/pubmed/29637811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19491034.2018.1454168
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