Nalaganje...
DNA repair defects and genome instability in Hutchinson-Gilford Progeria Syndrome
The integrity of the nuclear lamina has emerged as an important factor in the maintenance of genome stability. In particular, mutations in the LMNA gene, encoding A-type lamins (lamin A/C), alter nuclear morphology and function, and cause genomic instability. LMNA gene mutations are associated with...
Shranjeno v:
| izdano v: | Curr Opin Cell Biol |
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| Main Authors: | , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2015
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4522337/ https://ncbi.nlm.nih.gov/pubmed/26079711 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceb.2015.05.007 |
| Oznake: |
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