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Genomic Instability and DNA Damage Responses in Progeria Arising from Defective Maturation of Prelamin A

Progeria syndromes have in common a premature aging phenotype and increased genome instability. The susceptibility to DNA damage arises from a compromised repair system, either in the repair proteins themselves or in the DNA damage response pathways. The most severe progerias stem from mutations aff...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Musich, Phillip R., Zou, Yue
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Impact Journals LLC 2009
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2765059/
https://ncbi.nlm.nih.gov/pubmed/19851476
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