טוען...
The transcriptional coactivator CBP/p300 is an evolutionarily conserved node that promotes longevity in response to mitochondrial stress
Organisms respond to mitochondrial stress by activating multiple defense pathways including the mitochondrial unfolded protein response (UPR(mt)). However, how UPR(mt) regulators are orchestrated to transcriptionally activate stress responses remains largely unknown. Here we identified CBP-1, the wo...
שמור ב:
| הוצא לאור ב: | Nat Aging |
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| Main Authors: | , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2021
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7116894/ https://ncbi.nlm.nih.gov/pubmed/33718883 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s43587-020-00025-z |
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