Llwytho...
Bromodomain inhibition of the coactivators CBP/EP300 facilitate cellular reprogramming
Silencing of the somatic cell-type specific genes is a critical yet poorly understood step in reprogramming. To uncover pathways that maintain cell identity, we performed a reprogramming screen using inhibitors of chromatin factors. Here we identify acetyl-lysine competitive inhibitors targeting the...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | Nat Chem Biol |
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| Prif Awduron: | , , , , , , , , , , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
2019
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6504645/ https://ncbi.nlm.nih.gov/pubmed/30962627 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41589-019-0264-z |
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