TGF-β-stimulated cooperation of Smad proteins with the coactivators CBP/p300
TGF-β and activin induce the phosphorylation and activation of Smad2 and Smad3, but how these proteins stimulate gene transcription is poorly understood. We report that TGF-β receptor phosphorylation of Smad3 promotes its interaction with the paralogous coactivators CBP and p300, whereas CBP/p300 bi...
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| Gepubliceerd in: | Genes Dev |
|---|---|
| Hoofdauteurs: | , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Cold Spring Harbor Laboratory Press
1998
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC317012/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9679056/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.12.14.2114 |
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