TGF-β-stimulated cooperation of Smad proteins with the coactivators CBP/p300
TGF-β and activin induce the phosphorylation and activation of Smad2 and Smad3, but how these proteins stimulate gene transcription is poorly understood. We report that TGF-β receptor phosphorylation of Smad3 promotes its interaction with the paralogous coactivators CBP and p300, whereas CBP/p300 bi...
Gespeichert in:
| Veröffentlicht in: | Genes Dev |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Cold Spring Harbor Laboratory Press
1998
|
| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC317012/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9679056/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.12.14.2114 |
| Tags: |
Keine Tags, Fügen Sie das erste Tag hinzu!
|