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The p300/CBP acetyltransferases function as transcriptional coactivators of β-catenin in vertebrates

Wnt growth factors regulate a variety of developmental processes by altering specific gene expression patterns. In vertebrates β-catenin acts as transcriptional activator, which is needed to overcome target gene repression by Groucho/TLE proteins, and to permit promoter activation as the final conse...

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Bibliografische gegevens
Gepubliceerd in:EMBO J
Hoofdauteurs: Hecht, Andreas, Vleminckx, Kris, Stemmler, Marc P., van Roy, Frans, Kemler, Rolf
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2000
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC302022/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10775268/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/19.8.1839
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