TGF-β-stimulated cooperation of Smad proteins with the coactivators CBP/p300

TGF-β and activin induce the phosphorylation and activation of Smad2 and Smad3, but how these proteins stimulate gene transcription is poorly understood. We report that TGF-β receptor phosphorylation of Smad3 promotes its interaction with the paralogous coactivators CBP and p300, whereas CBP/p300 bi...

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Hlavní autoři: Janknecht, Ralf, Wells, Nicholas J., Hunter, Tony
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 1998
Témata:
Research Communication
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC317012/
https://ncbi.nlm.nih.gov/pubmed/9679056
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