The transcriptional coactivator CBP/p300 is an evolutionarily conserved node that promotes longevity in response to mitochondrial stress

Organisms respond to mitochondrial stress by activating multiple defense pathways including the mitochondrial unfolded protein response (UPR(mt)). However, how UPR(mt) regulators are orchestrated to transcriptionally activate stress responses remains largely unknown. Here we identified CBP-1, the wo...

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Detalhes bibliográficos
Publicado no:Nat Aging
Main Authors: Li, Terytty Yang, Sleiman, Maroun Bou, Li, Hao, Gao, Arwen W., Mottis, Adrienne, Bachmann, Alexis Maximilien, El Alam, Gaby, Li, Xiaoxu, Goeminne, Ludger J. E., Schoonjans, Kristina, Auwerx, Johan
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7116894/
https://ncbi.nlm.nih.gov/pubmed/33718883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s43587-020-00025-z
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