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Molecular basis of β-arrestin coupling to formoterol-bound β(1)-adrenoceptor
The β(1)-adrenoceptor (β(1)AR) is a G-protein-coupled receptor (GPCR) that couples(1) to the heterotrimeric G protein G(s). G-protein-mediated signalling is terminated by phosphorylation of the C terminus of the receptor by GPCR kinases (GRKs) and by coupling of β-arrestin 1 (βarr1, also known as ar...
Guardat en:
| Publicat a: | Nature |
|---|---|
| Autors principals: | , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7115876/ https://ncbi.nlm.nih.gov/pubmed/32555462 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-020-2419-1 |
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