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Structure and function of β-arrestins, their emerging role in breast cancer, and potential opportunities for therapeutic manipulation
β-Arrestins (βarrs) are multifunctional intracellular proteins with an ability to directly interact with a large number of cellular partners including the G protein-coupled receptors (GPCRs). βarrs contribute to multiple aspects of GPCR signaling, trafficking and downregulation. Considering the cent...
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| Udgivet i: | Adv Cancer Res |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7115872/ https://ncbi.nlm.nih.gov/pubmed/32089163 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.acr.2020.01.001 |
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