ENL initiates multivalent phase separation of the super elongation complex (SEC) in controlling rapid transcriptional activation

Release of paused RNA polymerase II (Pol II) requires incorporation of the positive transcription elongation factor b (P-TEFb) into the super elongation complex (SEC), thus resulting in rapid yet synchronous transcriptional activation. However, the mechanism underlying dynamic transition of P-TEFb f...

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Publicat a:Sci Adv
Autors principals: Guo, Chenghao, Che, Zhuanzhuan, Yue, Junjie, Xie, Peng, Hao, Shaohua, Xie, Wei, Luo, Zhuojuan, Lin, Chengqi
Format: Artigo
Idioma:Inglês
Publicat: American Association for the Advancement of Science 2020
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7112754/
https://ncbi.nlm.nih.gov/pubmed/32270036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aay4858
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