The Super Elongation Complex Family of RNA Polymerase II Elongation Factors: Gene Target Specificity and Transcriptional Output

The elongation stage of transcription is highly regulated in metazoans. We previously purified the AFF1- and AFF4-containing super elongation complex (SEC) as a major regulator of development and cancer pathogenesis. Here, we report the biochemical isolation of SEC-like 2 (SEC-L2) and SEC-like 3 (SE...

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Main Authors: Luo, Zhuojuan, Lin, Chengqi, Guest, Erin, Garrett, Alexander S., Mohaghegh, Nima, Swanson, Selene, Marshall, Stacy, Florens, Laurence, Washburn, Michael P., Shilatifard, Ali
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2012
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3434493/
https://ncbi.nlm.nih.gov/pubmed/22547686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00182-12
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