ENL initiates multivalent phase separation of the super elongation complex (SEC) in controlling rapid transcriptional activation

Release of paused RNA polymerase II (Pol II) requires incorporation of the positive transcription elongation factor b (P-TEFb) into the super elongation complex (SEC), thus resulting in rapid yet synchronous transcriptional activation. However, the mechanism underlying dynamic transition of P-TEFb f...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Sci Adv
Main Authors: Guo, Chenghao, Che, Zhuanzhuan, Yue, Junjie, Xie, Peng, Hao, Shaohua, Xie, Wei, Luo, Zhuojuan, Lin, Chengqi
Format: Artigo
Jezik:Inglês
Izdano: American Association for the Advancement of Science 2020
Teme:
Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7112754/
https://ncbi.nlm.nih.gov/pubmed/32270036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aay4858
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