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Treatment With Anti-C5a Antibody Improves the Outcome of H7N9 Virus Infection in African Green Monkeys

Background. Patients infected with influenza A(H7N9) virus present with acute lung injury (ALI) that is due to severe pneumonia and systemic inflammation. It is often fatal because there are few effective treatment options. Complement activation has been implicated in the pathogenesis of virus-induc...

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Bibliographic Details
Published in:Clin Infect Dis
Main Authors: Sun, Shihui, Zhao, Guangyu, Liu, Chenfeng, Fan, Wei, Zhou, Xiaojun, Zeng, Lin, Guo, Yan, Kou, Zhihua, Yu, Hong, Li, Junfeng, Wang, Renxi, Li, Yan, Schneider, Conny, Habel, Maria, Riedemann, Niels C., Du, Lanying, Jiang, Shibo, Guo, Renfeng, Zhou, Yusen
Format: Artigo
Language:Inglês
Published: Oxford University Press 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7112341/
https://ncbi.nlm.nih.gov/pubmed/25433014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cid/ciu887
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