Treatment With Anti-C5a Antibody Improves the Outcome of H7N9 Virus Infection in African Green Monkeys

Background. Patients infected with influenza A(H7N9) virus present with acute lung injury (ALI) that is due to severe pneumonia and systemic inflammation. It is often fatal because there are few effective treatment options. Complement activation has been implicated in the pathogenesis of virus-induc...

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Veröffentlicht in:Clin Infect Dis
Hauptverfasser: Sun, Shihui, Zhao, Guangyu, Liu, Chenfeng, Fan, Wei, Zhou, Xiaojun, Zeng, Lin, Guo, Yan, Kou, Zhihua, Yu, Hong, Li, Junfeng, Wang, Renxi, Li, Yan, Schneider, Conny, Habel, Maria, Riedemann, Niels C., Du, Lanying, Jiang, Shibo, Guo, Renfeng, Zhou, Yusen
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7112341/
https://ncbi.nlm.nih.gov/pubmed/25433014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cid/ciu887
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