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Of mice and men: murine bile acids explain species differences in the regulation of bile acid and cholesterol metabolism
Compared with humans, rodents have higher synthesis of cholesterol and bile acids (BAs) and faster clearance and lower levels of serum LDL-cholesterol. Paradoxically, they increase BA synthesis in response to bile duct ligation (BDL). Another difference is the production of hydrophilic 6-hydroxylate...
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| 出版年: | J Lipid Res |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The American Society for Biochemistry and Molecular Biology
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7112145/ https://ncbi.nlm.nih.gov/pubmed/32086245 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.RA119000307 |
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