A Physiology-Based Model of Bile Acid Distribution and Metabolism Under Healthy and Pathologic Conditions in Human Beings

BACKGROUND & AIMS: Disturbances of the enterohepatic circulation of bile acids (BAs) are seen in a number of clinically important conditions, including metabolic disorders, hepatic impairment, diarrhea, and gallstone disease. To facilitate the exploration of underlying pathogenic mechanisms, we...

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Publicat a:Cell Mol Gastroenterol Hepatol
Autors principals: Voronova, Veronika, Sokolov, Victor, Al-Khaifi, Amani, Straniero, Sara, Kumar, Chanchal, Peskov, Kirill, Helmlinger, Gabriel, Rudling, Mats, Angelin, Bo
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2020
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7240226/
https://ncbi.nlm.nih.gov/pubmed/32112828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmgh.2020.02.005
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