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Interpretation of metabolic memory phenomenon using a physiological systems model: What drives oxidative stress following glucose normalization?

Hyperglycemia is generally associated with oxidative stress, which plays a key role in diabetes-related complications. A complex, quantitative relationship has been established between glucose levels and oxidative stress, both in vitro and in vivo. For example, oxidative stress is known to persist a...

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Veröffentlicht in:PLoS One
Hauptverfasser: Voronova, Veronika, Zhudenkov, Kirill, Helmlinger, Gabriel, Peskov, Kirill
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5298285/
https://ncbi.nlm.nih.gov/pubmed/28178319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0171781
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