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Of mice and men: murine bile acids explain species differences in the regulation of bile acid and cholesterol metabolism

Compared with humans, rodents have higher synthesis of cholesterol and bile acids (BAs) and faster clearance and lower levels of serum LDL-cholesterol. Paradoxically, they increase BA synthesis in response to bile duct ligation (BDL). Another difference is the production of hydrophilic 6-hydroxylate...

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Bibliografski detalji
Izdano u:J Lipid Res
Glavni autori: Straniero, Sara, Laskar, Amit, Savva, Christina, Härdfeldt, Jennifer, Angelin, Bo, Rudling, Mats
Format: Artigo
Jezik:Inglês
Izdano: The American Society for Biochemistry and Molecular Biology 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7112145/
https://ncbi.nlm.nih.gov/pubmed/32086245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.RA119000307
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