Treatment of AG129 mice with antisense morpholino oligomers increases survival time following challenge with dengue 2 virus

OBJECTIVES: To determine the antiviral activity of phosphorodiamidate morpholino oligomers (PMO) and peptide-conjugated PMO (PPMO) in AG129 mice infected with dengue 2 virus (DENV-2). METHODS: Antisense PMO and PPMO were designed against the 5′ terminal region (5′SL) or the 3′-cyclization sequence r...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Antimicrob Chemother
Main Authors: Stein, David A., Huang, Claire Y.-H., Silengo, Shawn, Amantana, Adams, Crumley, Stacy, Blouch, Robert E., Iversen, Patrick L., Kinney, Richard M.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2008
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7109848/
https://ncbi.nlm.nih.gov/pubmed/18567576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkn221
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados