Inhibition of alphavirus infection in cell culture and in mice with antisense morpholino oligomers

The genus Alphavirus contains members that threaten human health, both as natural pathogens and as potential biological weapons. Peptide-conjugated phosphorodiamidate morpholino oligomers (PPMO) enter cells readily and can inhibit viral replication through sequence-specific steric blockade of viral...

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Main Authors: Paessler, Slobodan, Rijnbrand, Rene, Stein, David A., Ni, Haolin, Yun, Nadezhda E., Dziuba, Natallia, Borisevich, Viktoriya, Seregin, Alexey, Ma, Yinghong, Blouch, Robert, Iversen, Patrick L., Zacks, Michele A.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier Inc. 2008
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2447162/
https://ncbi.nlm.nih.gov/pubmed/18468653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2008.03.032
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