Inhibition of Dengue Virus Serotypes 1 to 4 in Vero Cell Cultures with Morpholino Oligomers

Five dengue (DEN) virus-specific R(5)F(2)R(4) peptide-conjugated phosphorodiamidate morpholino oligomers (P4-PMOs) were evaluated for their ability to inhibit replication of DEN virus serotype 2 (DEN-2 virus) in mammalian cell culture. Initial growth curves of DEN-2 virus 16681 were obtained in Vero...

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Detalhes bibliográficos
Main Authors: Kinney, Richard M., Huang, Claire Y.-H., Rose, Becky C., Kroeker, Andrew D., Dreher, Theo W., Iversen, Patrick L., Stein, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1069583/
https://ncbi.nlm.nih.gov/pubmed/15795296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.8.5116-5128.2005
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