Inhibition of Multiple Subtypes of Influenza A Virus in Cell Cultures with Morpholino Oligomers

Peptide-conjugated phosphorodiamidate morpholino oligomers (P-PMO) are single-stranded nucleic acid-like antisense agents that can reduce gene expression by sterically blocking complementary RNA sequence. P-PMO are water soluble and nuclease resistant, and they readily achieve uptake into cells in c...

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Detalhes bibliográficos
Main Authors: Ge, Qing, Pastey, Manoj , Kobasa, Darwyn, Puthavathana, Piliapan, Lupfer, Christopher, Bestwick, Richard K. , Iversen, Patrick L., Chen, Jianzhu, Stein, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1635187/
https://ncbi.nlm.nih.gov/pubmed/16966399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00644-06
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