Inhibition, Escape, and Attenuated Growth of Severe Acute Respiratory Syndrome Coronavirus Treated with Antisense Morpholino Oligomers

The recently emerged severe acute respiratory syndrome coronavirus (SARS-CoV) is a potent pathogen of humans and is capable of rapid global spread. Peptide-conjugated antisense morpholino oligomers (P-PMO) were designed to bind by base pairing to specific sequences in the SARS-CoV (Tor2 strain) geno...

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Detalhes bibliográficos
Main Authors: Neuman, Benjamin W., Stein, David A., Kroeker, Andrew D., Churchill, Michael J., Kim, Alice M., Kuhn, Peter, Dawson, Philip, Moulton, Hong M., Bestwick, Richard K., Iversen, Patrick L., Buchmeier, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1181598/
https://ncbi.nlm.nih.gov/pubmed/16014928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.15.9665-9676.2005
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