Antisense Morpholino-Oligomers Directed against the 5′ End of the Genome Inhibit Coronavirus Proliferation and Growth†

Conjugation of a peptide related to the human immunodeficiency virus type 1 Tat represents a novel method for delivery of antisense morpholino-oligomers. Conjugated and unconjugated oligomers were tested to determine sequence-specific antiviral efficacy against a member of the Coronaviridae, Mouse h...

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Udgivet i:J Virol
Main Authors: Neuman, Benjamin W., Stein, David A., Kroeker, Andrew D., Paulino, Amy D., Moulton, Hong M., Iversen, Patrick L., Buchmeier, Michael J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2004
Fag:
Vaccines and Antiviral Agents
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC415795/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15140987/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.78.11.5891-5899.2004
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