Antisense Morpholino-Oligomers Directed against the 5′ End of the Genome Inhibit Coronavirus Proliferation and Growth†

Conjugation of a peptide related to the human immunodeficiency virus type 1 Tat represents a novel method for delivery of antisense morpholino-oligomers. Conjugated and unconjugated oligomers were tested to determine sequence-specific antiviral efficacy against a member of the Coronaviridae, Mouse h...

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Detalhes bibliográficos
Main Authors: Neuman, Benjamin W., Stein, David A., Kroeker, Andrew D., Paulino, Amy D., Moulton, Hong M., Iversen, Patrick L., Buchmeier, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC415795/
https://ncbi.nlm.nih.gov/pubmed/15140987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.11.5891-5899.2004
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