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Heat Shock Protein 22 Attenuates Doxorubicin-Induced Cardiotoxicity via Regulating Inflammation and Apoptosis

BACKGROUND: The antitumor effect of doxorubicin (DOX) is limited by its acute and chronic toxicity to the heart, which causes heart injury. Heat shock protein 22 (Hsp22) is a protein proved to exert anti-apoptosis and anti-inflammatory effects in other diseases and physical conditions. In this study...

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Vydáno v:Front Pharmacol
Hlavní autoři: Lan, Yin, Wang, Yi, Huang, Kun, Zeng, Qiutang
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7109316/
https://ncbi.nlm.nih.gov/pubmed/32269523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.00257
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