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Vincristine attenuates doxorubicin cardiotoxicity

Our aim was to test the hypothesis that the vinca alkaloid vincristine could prevent doxorubicin-induced cardiomyocyte death and to identify the mechanisms involved. Adult mouse cardiac myocytes were incubated for 24 h with doxorubicin, with and without concurrent vincristine. Trypan blue exclusion...

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Autori principali: Chatterjee, Kanu, Zhang, Jianqing, Tao, Rong, Honbo, Norman, Karliner, Joel S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2846088/
https://ncbi.nlm.nih.gov/pubmed/18590705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2008.06.067
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