Pyrroloquinoline Quinone Preserves Mitochondrial Function and Prevents Oxidative Injury in Adult Rat Cardiac Myocytes

We investigated the ability of pyrroloquinoline quinone (PQQ) to confer resistance to acute oxidative stress in freshly isolated adult male rat cardiomyocytes. Fluorescence microscopy was used to detect generation of reactive oxygen species (ROS) and mitochondrial membrane potential (Δψ(m)) depolari...

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Bibliographic Details
Main Authors: Tao, Rong, Karliner, Joel S., Simonis, Ursula, Zheng, Jie, Zhang, Jianqing, Honbo, Norman, Alano, Conrad C.
Format: Artigo
Language:Inglês
Published: 2007
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2844438/
https://ncbi.nlm.nih.gov/pubmed/17880922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2007.08.041
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