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Pyrroloquinoline Quinone Preserves Mitochondrial Function and Prevents Oxidative Injury in Adult Rat Cardiac Myocytes

We investigated the ability of pyrroloquinoline quinone (PQQ) to confer resistance to acute oxidative stress in freshly isolated adult male rat cardiomyocytes. Fluorescence microscopy was used to detect generation of reactive oxygen species (ROS) and mitochondrial membrane potential (Δψ(m)) depolari...

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Detalhes bibliográficos
Main Authors: Tao, Rong, Karliner, Joel S., Simonis, Ursula, Zheng, Jie, Zhang, Jianqing, Honbo, Norman, Alano, Conrad C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2844438/
https://ncbi.nlm.nih.gov/pubmed/17880922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2007.08.041
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