Pyrroloquinoline Quinone Preserves Mitochondrial Function and Prevents Oxidative Injury in Adult Rat Cardiac Myocytes

We investigated the ability of pyrroloquinoline quinone (PQQ) to confer resistance to acute oxidative stress in freshly isolated adult male rat cardiomyocytes. Fluorescence microscopy was used to detect generation of reactive oxygen species (ROS) and mitochondrial membrane potential (Δψ(m)) depolari...

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Bibliografiske detaljer
Main Authors: Tao, Rong, Karliner, Joel S., Simonis, Ursula, Zheng, Jie, Zhang, Jianqing, Honbo, Norman, Alano, Conrad C.
Format: Artigo
Sprog:Inglês
Udgivet: 2007
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2844438/
https://ncbi.nlm.nih.gov/pubmed/17880922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2007.08.041
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