Enoxaparin attenuates doxorubicin induced cardiotoxicity in rats via interfering with oxidative stress, inflammation and apoptosis

BACKGROUND: Doxorubicin (DOX) is commonly used in the treatment of many types of cancers but its cardiotoxicity is limiting its clinical use. Beyond its anticoagulant action, enoxaparin (ENX), a low molecular weight heparin, has been shown to exert multiple pharmacological actions including antioxid...

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Bibliographic Details
Published in:BMC Pharmacol Toxicol
Main Authors: Shaker, Reem Ali, Abboud, Samer Hassan, Assad, Hayder Chasib, Hadi, Najah
Format: Artigo
Language:Inglês
Published: BioMed Central 2018
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5763526/
https://ncbi.nlm.nih.gov/pubmed/29321061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40360-017-0184-z
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