Cystic fibrosis transmembrane conductance regulator dysfunction in platelets drives lung hyperinflammation

Cystic fibrosis (CF) lung disease is characterized by an inflammatory response that can lead to terminal respiratory failure. The cystic fibrosis transmembrane conductance regulator (CFTR) is mutated in CF, and we hypothesized that dysfunctional CFTR in platelets, which are key participants in immun...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Ortiz-Muñoz, Guadalupe, Yu, Michelle A., Lefrançais, Emma, Mallavia, Beñat, Valet, Colin, Tian, Jennifer J., Ranucci, Serena, Wang, Kristin M., Liu, Zhe, Kwaan, Nicholas, Dawson, Diana, Kleinhenz, Mary Ellen, Khasawneh, Fadi T., Haggie, Peter M., Verkman, Alan S., Looney, Mark R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7108932/
https://ncbi.nlm.nih.gov/pubmed/31961827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI129635
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados