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Heparan sulfate attachment receptor is a major selection factor for attenuated enterovirus 71 mutants during cell culture adaptation

Enterovirus 71 (EV71) is a causative agent of hand, foot, and mouth disease (HFMD). However, this infection is sometimes associated with severe neurological complications. Identification of neurovirulence determinants is important to understand the pathogenesis of EV71. One of the problems in evalua...

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Dades bibliogràfiques
Publicat a:PLoS Pathog
Autors principals: Kobayashi, Kyousuke, Mizuta, Katsumi, Koike, Satoshi
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7105141/
https://ncbi.nlm.nih.gov/pubmed/32187235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008428
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