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Heparan sulfate attachment receptor is a major selection factor for attenuated enterovirus 71 mutants during cell culture adaptation

Enterovirus 71 (EV71) is a causative agent of hand, foot, and mouth disease (HFMD). However, this infection is sometimes associated with severe neurological complications. Identification of neurovirulence determinants is important to understand the pathogenesis of EV71. One of the problems in evalua...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Kobayashi, Kyousuke, Mizuta, Katsumi, Koike, Satoshi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7105141/
https://ncbi.nlm.nih.gov/pubmed/32187235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008428
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