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Heparan sulfate attachment receptor is a major selection factor for attenuated enterovirus 71 mutants during cell culture adaptation

Enterovirus 71 (EV71) is a causative agent of hand, foot, and mouth disease (HFMD). However, this infection is sometimes associated with severe neurological complications. Identification of neurovirulence determinants is important to understand the pathogenesis of EV71. One of the problems in evalua...

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Detalles Bibliográficos
Publicado en:PLoS Pathog
Main Authors: Kobayashi, Kyousuke, Mizuta, Katsumi, Koike, Satoshi
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7105141/
https://ncbi.nlm.nih.gov/pubmed/32187235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008428
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