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Amino Acid Variation at VP1-145 of Enterovirus 71 Determines Attachment Receptor Usage and Neurovirulence in Human Scavenger Receptor B2 Transgenic Mice

Infection by enterovirus 71 (EV71) is affected by cell surface receptors, including the human scavenger receptor B2 (hSCARB2), which are required for viral uncoating, and attachment receptors, such are heparan sulfate (HS), which bind virus but do not support uncoating. Amino acid residue 145 of the...

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Vydáno v:J Virol
Hlavní autoři: Kobayashi, Kyousuke, Sudaka, Yui, Takashino, Ayako, Imura, Ayumi, Fujii, Ken, Koike, Satoshi
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6052303/
https://ncbi.nlm.nih.gov/pubmed/29848584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00681-18
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