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SENP1 regulates IFN-γ−STAT1 signaling through STAT3−SOCS3 negative feedback loop
Interferon-γ (IFN-γ) triggers macrophage for inflammation response by activating the intracellular JAK−STAT1 signaling. Suppressor of cytokine signaling 1 (SOCS1) and protein tyrosine phosphatases can negatively modulate IFN-γ signaling. Here, we identify a novel negative feedback loop mediated by S...
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| Publicado no: | J Mol Cell Biol |
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| Main Authors: | , , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7104919/ https://ncbi.nlm.nih.gov/pubmed/27702761 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jmcb/mjw042 |
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